An applicator may be harmed by pesticide exposure by experiencing:

• A. Several exposures over time
• B. A single brief contact
• C. Exposure in a cold room
• D. Severe reactions immediately

Answer: (D)

An applicator is harmed when exposure triggers an immediate, severe reaction. Acute pesticide poisoning can occur from a single contact, especially with highly toxic formulations or rapid skin or inhalation absorption. When severe symptoms appear right away—such as trouble breathing, confusion, seizures, or fainting—that immediate onset clearly shows harm from the exposure and requires urgent care.

While multiple exposures over time can cause harm through cumulative effects, and certain conditions like a cold room don’t inherently change the toxic effect in a direct, immediate way, and a single brief contact can be harmful in some cases, the strongest indicator of harm in this scenario is an immediate, severe reaction.